Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931344 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2ACDK1 | |
| SCHEMBL6930001 | 0.82 | ALDH1A1 (0.45) | ALDH1A1LMNAMEN1KMT2ACDK1 | |
| SCHEMBL6026587 | 0.81 | ALDH1A1 (0.43) | EGFRALDH1A1LMNASMN1; SMN2CA1 | |
| SCHEMBL7030920 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNACDK1CCNB1GSK3A | |
| SCHEMBL6933633 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNAMEN1KMT2ACDK1 | |
| SCHEMBL9015283 | 0.79 | LMNA (0.43) | ALDH1A1LMNACDK1CCNB1GSK3A | |
| SCHEMBL8993559 | 0.79 | LMNA (0.43) | ALDH1A1LMNACDK1CCNB1GSK3A | |
| SCHEMBL6025954 | 0.78 | ALDH1A1 (0.46) | EGFRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7591786 | 0.75 | AHR (0.41) | ALDH1A1LMNAMEN1KMT2ACDK1 | |
| SCHEMBL6933173 | 0.75 | AHR (0.41) | ALDH1A1LMNAMEN1KMT2ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |