Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 3/20 | 0.42 |
| ▸ | MERTK | Q12866 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344471 | 1.00 | ACHE (0.45) | ACHEL3MBTL1SMN1; SMN2ADRA2CDRD4 | |
| SCHEMBL7966936 | 0.89 | ALDH1A1 (0.54) | ACHEL3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7966930 | 0.89 | ALDH1A1 (0.54) | ACHEL3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7966929 | 0.89 | ALDH1A1 (0.54) | ACHEL3MBTL1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL28343422 | 0.85 | DRD4 (0.48) | ADRA2CDRD4MAPTALDH1A1AXL | |
| SCHEMBL20203110 | 0.85 | DRD4 (0.48) | ADRA2CDRD4MAPTALDH1A1AXL | |
| SCHEMBL15341452 | 0.83 | DRD4 (0.42) | SMN1; SMN2ADRA2CDRD4ALDH1A1MEN1 | |
| SCHEMBL15341455 | 0.83 | DRD4 (0.42) | SMN1; SMN2ADRA2CDRD4ALDH1A1MEN1 | |
| SCHEMBL17432746 | 0.83 | ADRA2C (0.62) | ADRA2CDRD4ALDH1A1GLA | |
| SCHEMBL12180342 | 0.82 | PDE10A (0.51) | ACHESMN1; SMN2DRD4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933103-B2 | Pyridone derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-01-13 | — | — | US | disclosed |
| US-20130281428-A1 | Pyridone Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281428-A1 | Pyridone Derivatives | AXL, PDXK, TYRO3 | ACHE 2787/4885L3MBTL1 665/4885SMN1; SMN2 2627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.