Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 4/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.38 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.38 |
| ▸ | CPT1A | P50416 | 2/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967019 | 0.93 | CPT1A (0.34) | AVPR2AVPR1AAVPR1BCPT1ACPT1B | |
| SCHEMBL7971950 | 0.90 | AVPR2 (0.41) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7969564 | 0.86 | MAPK11 (0.37) | AVPR2AVPR1AAVPR1BCPT1ACPT1B | |
| SCHEMBL7339871 | 0.85 | ALDH1A1 (0.39) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7975518 | 0.83 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7964569 | 0.83 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7341082 | 0.83 | PDE4A (0.41) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL7973515 | 0.83 | AVPR2 (0.37) | AVPR2AVPR1AAVPR1BTP53 | |
| SCHEMBL7953703 | 0.82 | AVPR2 (0.39) | AVPR2AVPR1AAVPR1BADRA1DADRA1A | |
| SCHEMBL7345034 | 0.82 | AVPR2 (0.40) | AVPR2AVPR1AAVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316482-B1 | FOR THERAPY AND PROPHYLAXIS OF HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME, HEPATOCIRRHOSIS, HYPONATREMIA, HYPOKALEMIA, DIABETIC, CIRCULATION DISORDER, CEREBROVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |