Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | ME2 | P23368 | 1/20 | 0.40 |
| ▸ | ME1 | P48163 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29913819 | 0.81 | KDM4E (0.57) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL897607 | 0.80 | KDM4E (0.55) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL10948548 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| Bicarbonate SCHEMBL28996502 | 0.78 | TDP1 (0.58) | KDM4EMEN1KMT2AHPGDCYP1A2 | |
| SCHEMBL6844838 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| Ammonia Solution, Strong SCHEMBL7720474 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL8574060 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL2507677 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| Ammonia Solution, Strong SCHEMBL7720478 | 0.78 | KDM4E (0.53) | KDM4EMEN1KMT2AALDH1A1GLA | |
| SCHEMBL8463438 | 0.77 | MEN1 (0.49) | KDM4EMEN1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277867-B1 | SYNERGISTIC MIXTURES | CHINOIN GYOGYSZER ES VEGYESZETI (HU) | 2001-08-21 | — | — | US | disclosed |