Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20560274 | 0.83 | AKR1B1 (0.42) | IDO1ALDH1A1KDM4EATMMAOB | |
| SCHEMBL6814075 | 0.82 | IDO1 (0.48) | IDO1ALDH1A1KDM4EATMHSD11B1 | |
| SCHEMBL121915 | 0.80 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMMAOB | |
| SCHEMBL29560223 | 0.80 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMMAOB | |
| SCHEMBL10747351 | 0.79 | P2RX7 (0.46) | IDO1P2RX7 | |
| SCHEMBL5097748 | 0.79 | IDO1 (0.44) | IDO1ALDH1A1KDM4EATMHSD11B1 | |
| SCHEMBL21312967 | 0.79 | GABRA1 (0.46) | IDO1HSD11B1MAOBPOLBSMN1; SMN2 | |
| SCHEMBL3238101 | 0.79 | IDO1 (0.41) | IDO1ALDH1A1KDM4EATMHSD11B1 | |
| SCHEMBL144963 | 0.79 | IDO1 (0.41) | IDO1ALDH1A1KDM4EATMHSD11B1 | |
| SCHEMBL30368290 | 0.79 | IDO1 (0.41) | IDO1ALDH1A1KDM4EATMHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207826-B1 | Macrocyclic compounds having nitrogen-containing linkages | ISIS PHARMACEUTICALS, INC. | 2001-03-27 | — | — | US | disclosed |