Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29427013 | 0.82 | IDO1 (0.57) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL4527 | 0.82 | IDO1 (0.57) | IDO1MAOBALDH1A1POLBTDP1 | |
| SCHEMBL29452402 | 0.79 | HCAR1 (0.34) | IDO1 | |
| SCHEMBL841044 | 0.79 | AKR1B1 (0.42) | IDO1P2RX7MAOBALDH1A1POLB | |
| SCHEMBL30806616 | 0.79 | AKR1B1 (0.42) | IDO1P2RX7MAOBALDH1A1POLB | |
| SCHEMBL3238101 | 0.79 | IDO1 (0.41) | IDO1HSD11B1MAOBALDH1A1POLB | |
| SCHEMBL5097748 | 0.79 | IDO1 (0.44) | IDO1HSD11B1MAOBALDH1A1POLB | |
| SCHEMBL7967045 | 0.79 | IDO1 (0.41) | IDO1P2RX7HSD11B1MAOBALDH1A1 | |
| SCHEMBL21312967 | 0.79 | GABRA1 (0.46) | IDO1HSD11B1MAOBPOLBKMT2A | |
| SCHEMBL30368290 | 0.79 | IDO1 (0.41) | IDO1HSD11B1MAOBALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250304579-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-10-02 | — | — | US | disclosed |
| US-12227503-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-02-18 | — | — | US | disclosed |
| US-12006305-B2 | Salts of obicetrapib and processes for their manufacture and intermediates thereof | NEWAMSTERDAM PHARMA B.V. (NL) | 2024-06-11 | — | — | US | disclosed |
| WO-2024042061-A1 | OBICETRAPIB AND EZETIMIBE COMBINATION TREATMENT AND FIXED DOSE PHARMACEUTICAL COMPOSITIONS | NEWAMSTERDAM PHARMA B.V. (NL) | 2024-02-29 | — | — | WO | disclosed |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-01-25 | — | — | US | disclosed |
| WO-2024009144-A1 | SALTS OF OBICETRAPIB AND PROCESSES FOR THEIR MANUFACTURE AND INTERMEDIATES THEREOF | NEWAMSTERDAM PHARMA B.V. (NL) | 2024-01-11 | — | — | WO | disclosed |
| US-20240010630-A1 | Salts of Obicetrapib and Processes for their Manufacture and Intermediates Thereof | NEWAMSTERDAM PHARMA B.V. (NL) | 2024-01-11 | — | — | US | disclosed |
| US-11787804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-04-13 | — | — | US | disclosed |
| US-11472804-B2 | Compositions and methods for modulating hair growth | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-10-18 | — | — | US | disclosed |
| WO-1998008818-A1 | INHIBITORS OF PHOSPHOLIPASE ENZYMES | GENETICS INSTITUTE, INC. (US) | 1998-03-05 | — | — | WO | disclosed |
| US-5719156-A | ASTHMA | SCHERING CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |
| EP-0499313-B1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME (GB) | 1997-06-11 | — | — | EP | disclosed |
| US-5554633-A | ANTIINFLAMMATORY, ANTIARTHRITIC, AND ANALGESIC AGENTS; MIGRAINE | MERCK, SHARP & DOHME, LTD. (GB) | 1996-09-10 | — | — | US | disclosed |
| EP-0636130-A1 | AZACYCLIC COMPOUNDS | MERCK SHARP & DOHME LTD. (GB) | 1995-02-01 | — | — | EP | disclosed |
| EP-0600952-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | MERCK SHARP & DOHME (GB) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994003429-A1 | SUBSTITUTED AMINES AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1994-02-17 | — | — | WO | disclosed |
| US-5242930-A | AZABICYCLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. | 1993-09-07 | — | — | US | disclosed |
| WO-1993004040-A1 | AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | MERCK SHARP & DOHME LIMITED (GB) | 1993-03-04 | — | — | WO | disclosed |
| EP-0499313-A1 | Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy | MERCK SHARP & DOHME LTD. (GB) | 1992-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12006305-B2 | Salts of obicetrapib and processes for their manufacture and intermediates thereof | OSTC, SOST, OCIAD1 | IDO1 4266/4885P2RX7 381/4885HSD11B1 1380/4885 |
| US-20230114220-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
| US-11472804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
| US-20250304579-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
| US-11787804-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
| US-20240010630-A1 | Salts of Obicetrapib and Processes for their Manufacture and Intermediates Thereof | OSTC, SOST, OCIAD1 | IDO1 4266/4885P2RX7 381/4885HSD11B1 1380/4885 |
| US-20240025895-A1 | COMPOSITIONS AND METHODS FOR MODULATING HAIR GROWTH | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
| US-12227503-B2 | Compositions and methods for modulating hair growth | PC, FH, SLC25A1 | IDO1 981/4885P2RX7 2705/4885HSD11B1 468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.