Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202300 | 0.90 | CHRM2 (0.46) | NCF1SLC6A4CHRM2CHRM4CHRM5 | |
| SCHEMBL17844553 | 0.79 | MEN1 (0.38) | PLD1SLC6A4KCNA5KCNH2CHRM2 | |
| Hydrochloric Acid SCHEMBL17844468 | 0.78 | CHRM4 (0.39) | PLD1KCNA5KCNH2CHRM2CHRM4 | |
| SCHEMBL2697321 | 0.75 | CYP2B6 (0.66) | NCF1KCNA5KCNH2CHRM2CHRM4 | |
| SCHEMBL17810248 | 0.73 | CYP2B6 (0.67) | SLC6A4KCNH2CHRM2CHRM4CHRM5 | |
| SCHEMBL2431449 | 0.73 | CYP2B6 (0.43) | NCF1KCNA5KCNH2CHRM2CHRM4 | |
| SCHEMBL5139721 | 0.73 | OPRD1 (0.49) | KCNA5KCNH2CHRM2CHRM4CHRM5 | |
| SCHEMBL7317038 | 0.72 | SIGMAR1 (0.46) | ADRB2NCF1SLC6A4CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL11447338 | 0.71 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL569963 | 0.71 | SIGMAR1 (0.48) | NCF1CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |