Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 20/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439147 | 0.73 | FABP3 (0.48) | PTPN11 | |
| SCHEMBL18680220 | 0.70 | KMT2A (0.47) | PTPN11 | |
| SCHEMBL7979540 | 0.70 | KMT2A (0.39) | PTPN11 | |
| SCHEMBL28402122 | 0.67 | LMNA (0.50) | — | |
| SCHEMBL6951228 | 0.67 | SMN1; SMN2 (0.49) | PTPN11 | |
| SCHEMBL30587182 | 0.67 | SMN1; SMN2 (0.49) | PTPN11 | |
| SCHEMBL7967602 | 0.61 | CACNB4 (0.39) | PTPN11 | |
| SCHEMBL28402121 | 0.61 | LMNA (0.51) | — | |
| SCHEMBL10913994 | 0.60 | KMT2A (0.43) | — | |
| SCHEMBL7977566 | 0.59 | HTT (0.42) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |