Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 15/20 | 0.38 |
| ▸ | FABP3 | P05413 | 2/20 | 0.37 |
| ▸ | FABP4 | P15090 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439147 | 0.79 | FABP3 (0.48) | KMT2APTPN11FABP3FABP4DHODH | |
| SCHEMBL18680220 | 0.76 | KMT2A (0.47) | KMT2APTPN11FABP3FABP4DHODH | |
| SCHEMBL30587182 | 0.72 | SMN1; SMN2 (0.49) | KMT2APTPN11FABP3FABP4ALDH1A1 | |
| SCHEMBL6951228 | 0.72 | SMN1; SMN2 (0.49) | KMT2APTPN11FABP3FABP4ALDH1A1 | |
| SCHEMBL7967357 | 0.70 | PTPN11 (0.38) | PTPN11 | |
| SCHEMBL28402122 | 0.67 | LMNA (0.50) | KMT2AFABP3FABP4ALDH1A1MAPT | |
| SCHEMBL10913994 | 0.67 | KMT2A (0.43) | KMT2AFABP3FABP4DHODHALDH1A1 | |
| SCHEMBL7979537 | 0.65 | POLB (0.44) | KMT2APTPN11ALDH1A1MAPT | |
| SCHEMBL7977551 | 0.65 | DHODH (0.37) | KMT2APTPN11FABP3FABP4DHODH | |
| SCHEMBL29771130 | 0.63 | KMO (0.44) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |