Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.39 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CACNA1E | Q15878 | 1/20 | 0.39 |
| ▸ | CACNA2D4 | Q7Z3S7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600882 | 0.85 | CACNB4 (0.43) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7979243 | 0.85 | CACNB4 (0.38) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7977502 | 0.83 | CYP1A2 (0.53) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7981180 | 0.83 | CACNB4 (0.38) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7981539 | 0.82 | SLC6A2 (0.44) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7977490 | 0.81 | LMNA (0.55) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL10748512 | 0.75 | SMN1; SMN2 (0.42) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL11009475 | 0.75 | CACNA1C (0.45) | CACNB4CACNA1ACACNA1GCACNG3CACNA1F | |
| SCHEMBL7979537 | 0.73 | POLB (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2PTPN11 | |
| SCHEMBL7984066 | 0.73 | POLB (0.44) | ALDH1A1LMNAHPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |