Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PLK1 | P53350 | 8/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6129596 | 0.88 | PPARG (0.45) | PPARGPLA2G2APLA2G1B | |
| SCHEMBL7967407 | 0.86 | PLA2G2A (0.43) | PPARGPLA2G2APLA2G1B | |
| SCHEMBL7967406 | 0.85 | PPARG (0.35) | PPARGPLK1ICMTCNR2CNR1 | |
| SCHEMBL27526509 | 0.84 | PPARG (0.35) | PPARGPLK1PLK3ICMTCNR2 | |
| SCHEMBL6778663 | 0.81 | CNR2 (0.42) | PPARGCNR2CNR1PLA2G2A | |
| SCHEMBL27526530 | 0.81 | CNR2 (0.34) | PPARGICMTCNR2CNR1GRIN2B | |
| SCHEMBL6770304 | 0.79 | CNR1 (0.42) | PPARGICMTCNR2CNR1PLA2G2A | |
| SCHEMBL7965914 | 0.78 | PLA2G2A (0.51) | PPARGPLA2G2APLA2G1B | |
| SCHEMBL7962764 | 0.78 | PLA2G2A (0.33) | PPARGPLA2G2A | |
| SCHEMBL27526178 | 0.77 | PPARG (0.35) | PPARGCNR2GRIN2BPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |