Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7962769 | 0.85 | PLA2G2A (0.42) | PLA2G2A | |
| SCHEMBL7962766 | 0.84 | ABCC1 (0.32) | PLA2G2AABCC1MAPK14PPARG | |
| SCHEMBL28740799 | 0.82 | PPARG (0.32) | ABCC1MAPK14PPARGCYP3A4 | |
| SCHEMBL6129596 | 0.78 | PPARG (0.45) | PLA2G2APPARG | |
| SCHEMBL7967403 | 0.78 | PPARG (0.36) | PLA2G2APPARG | |
| SCHEMBL27526622 | 0.77 | AGTR1 (0.33) | ABCC1MAPK14PPARGCYP3A4AGTR1 | |
| SCHEMBL27505302 | 0.77 | PPARG (0.35) | ABCC1PPARGAGTR1AGTR2 | |
| SCHEMBL27506349 | 0.76 | MAPK14 (0.32) | PLA2G2AABCC1MAPK14CYP3A4 | |
| SCHEMBL29029763 | 0.76 | AURKA (0.41) | PLA2G2A | |
| SCHEMBL30410352 | 0.76 | AURKA (0.41) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177440-B1 | THERAPY FOR SEPSIS SHOCK; PHOSPHOLIPASE INHBITOR | ELI LILLY AND COMPANY | 2001-01-23 | — | — | US | disclosed |