Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 8/20 | 0.60 |
| ▸ | GAA | P10253 | 8/20 | 0.60 |
| ▸ | SI | P14410 | 8/20 | 0.60 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1348944 | 0.86 | MGAM (0.64) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL14168804 | 0.84 | GPR84 (0.64) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL13253129 | 0.83 | MEN1 (0.74) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL27682946 | 0.83 | GPR84 (0.62) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL108954 | 0.80 | GPR84 (0.84) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL5186684 | 0.80 | CYP2D6 (0.67) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL2073813 | 0.80 | CYP2D6 (0.67) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL15148952 | 0.79 | MGAM (0.76) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL1348083 | 0.79 | CYP2D6 (0.57) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 | |
| SCHEMBL2465013 | 0.79 | SLC6A2 (0.57) | GPR84CYP2D6SLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232307-B1 | 2-PHENYL-1-(4-(2-AMINOETHOXY)-BENZYL)-INDOLE COMPOUNDS USEFUL AS ESTROGENIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-05-15 | — | — | US | disclosed |