Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117481 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL14098034 | 0.83 | ACHE (0.37) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL14098015 | 0.81 | CYP1A2 (0.38) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL14138485 | 0.80 | ACHE (0.35) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL7112968 | 0.76 | KMT2A (0.61) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5640862 | 0.75 | KMT2A (0.63) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL4480344 | 0.73 | KMT2A (0.53) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL7115046 | 0.73 | ABCG2 (0.52) | ALDH1A1HPGDKDM4ECYP3A4MAPK1 | |
| SCHEMBL8377609 | 0.72 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL7110256 | 0.72 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | claimed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | claimed |
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |