Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.48 |
| ▸ | BCHE | P06276 | 3/20 | 0.45 |
| ▸ | BACE1 | P56817 | 6/20 | 0.45 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967827 | 1.00 | CTSK (0.48) | CTSKBCHEBACE1SLC6A11NPC1 | |
| SCHEMBL7698179 | 0.86 | TRPM8 (0.56) | CTSKBCHEBACE1SLC6A11CTSL | |
| SCHEMBL4910315 | 0.86 | TRPM8 (0.56) | CTSKBCHEBACE1SLC6A11CTSL | |
| SCHEMBL24324236 | 0.86 | TRPM8 (0.56) | CTSKBCHEBACE1SLC6A11CTSL | |
| SCHEMBL5413813 | 0.86 | TRPM8 (0.56) | CTSKBCHEBACE1SLC6A11CTSL | |
| SCHEMBL14395196 | 0.85 | BACE1 (0.51) | BCHEBACE1SLC6A11KLK5 | |
| SCHEMBL5863316 | 0.81 | TRPM8 (0.53) | CTSKBCHEBACE1ENPP2CTSL | |
| SCHEMBL5863319 | 0.81 | TRPM8 (0.53) | CTSKBCHEBACE1ENPP2CTSL | |
| SCHEMBL2188440 | 0.81 | BACE1 (0.54) | BCHEBACE1SLC6A11 | |
| SCHEMBL3324386 | 0.81 | BACE1 (0.54) | BCHEBACE1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012599-A1 | NEW ETHYLAZIRIDINE DERIVATIVES AND THEIR PREPARATION METHODS | SAMCHULLY PHARM CO., LTD. (KR) | 2001-02-22 | — | — | WO | disclosed |