Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.73 |
| ▸ | CES1 | P23141 | 2/20 | 0.73 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.50 |
| ▸ | VNN1 | O95497 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332679 | 0.89 | ATM (0.61) | CES2CES1HSD17B14VNN1KMT2A | |
| SCHEMBL13991056 | 0.87 | CES2 (0.57) | CES2CES1HSD17B14VNN1KMT2A | |
| SCHEMBL8845773 | 0.87 | ALDH1A1 (0.64) | CES2CES1KMT2AMEN1SLC6A2 | |
| SCHEMBL5684908 | 0.85 | CES2 (0.55) | CES2CES1HSD17B14VNN1KMT2A | |
| SCHEMBL29798141 | 0.84 | CES1 (1.00) | CES2CES1KMT2AMEN1CHRNA1 | |
| SCHEMBL1002846 | 0.84 | CES2 (0.53) | CES2CES1HSD17B14VNN1KMT2A | |
| SCHEMBL13664921 | 0.84 | CES2 (0.53) | CES2CES1HSD17B14VNN1KMT2A | |
| Hydrochloric Acid SCHEMBL10459098 | 0.84 | LTA4H (0.63) | CES2CES1VNN1KMT2AMEN1 | |
| SCHEMBL7802223 | 0.82 | CES2 (0.52) | CES2CES1HSD17B14VNN1KMT2A | |
| SCHEMBL6113460 | 0.82 | HPGD (0.62) | CES2CES1VNN1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63188643-A | — | — | None | — | — | JP | disclosed |
| CN-109400610-A | Pyrrolo-triazine analog derivative, preparation method and its purposes in medicine | 浙江海正药业股份有限公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-104940202-B | Inhibitors of influenza viruses replication | 沃泰克斯药物股份有限公司 | 2018-10-16 | — | — | CN | disclosed |
| CN-107278205-A | Substituted nucleoside derivates as anticarcinogen | 辉瑞大药厂 | 2017-10-20 | — | — | CN | disclosed |
| US-9522364-B2 | Treated mixed matrix polymeric membranes | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-12-20 | — | — | US | disclosed |
| US-9522364-B2 | Treated mixed matrix polymeric membranes | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-12-20 | — | — | US | disclosed |
| US-9492785-B2 | UV and thermally treated polymeric membranes | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-11-15 | — | — | US | disclosed |
| US-9492785-B2 | UV and thermally treated polymeric membranes | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-11-15 | — | — | US | disclosed |
| US-20160263533-A1 | TREATED MIXED MATRIX POLYMERIC MEMBRANES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-09-15 | — | — | US | disclosed |
| US-20160263531-A1 | PLASMA-TREATED POLYMERIC MEMBRANES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-09-15 | — | — | US | disclosed |
| US-7758751-B1 | UV-cross-linked membranes from polymers of intrinsic microporosity for liquid separations | UOP LLC (US) | 2010-07-20 | — | — | US | disclosed |
| US-7690514-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2010-04-06 | — | — | US | disclosed |
| US-7690514-B2 | Microporous polymer material | THE UNIVERSITY OF MANCHESTER (GB) | 2010-04-06 | — | — | US | disclosed |
| US-6274583-B1 | Alpha 1a adrenergic receptor antagonists | MERCK & CO., INC. | 2001-08-14 | — | — | US | disclosed |
| US-5977115-A | Alpha 1a adrenergic receptor antagonists | MERCK & CO., INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0833637-A4 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0833637-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996040136-A1 | ALPHA 1a ADRENERGIC RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4876382-A | Process for making fluorobenzoic acid fluorophenylesters | CENTRAL GLASS COMPANY, LIMITED (JP) | 1989-10-24 | — | — | US | disclosed |
| JP-S63188643-A | NOVEL FLUORINE-CONTAINING BENZOPHENONE AND PRODUCTION THEREOF | CENTRAL GLASS CO LTD | 1988-08-04 | — | — | JP | disclosed |