Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984491 | 0.88 | ABCC1 (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL8805027 | 0.84 | CACNA1F (0.40) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL7967817 | 0.82 | KDM4E (0.64) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL8817305 | 0.82 | BRD4 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL10895180 | 0.79 | CACNA1F (0.76) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL11005916 | 0.75 | CACNA1F (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL8340560 | 0.74 | CACNA1F (0.69) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL10830288 | 0.71 | KDM4E (0.79) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL29944536 | 0.71 | KDM4E (0.79) | CACNA1FCACNA1DCACNA1SCACNA1CHPGD | |
| SCHEMBL8082470 | 0.70 | ALOX15 (0.51) | CACNA1CHPGDKDM4ENPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |