Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968037 | 0.88 | CACNA1F (0.52) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8082470 | 0.82 | ALOX15 (0.51) | CACNA1CGAAADORA2BMEN1KMT2A | |
| SCHEMBL8817305 | 0.79 | BRD4 (0.39) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL8805027 | 0.79 | CACNA1F (0.40) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10113131 | 0.73 | GAA (0.79) | GAAADORA2BMEN1KMT2APOLB | |
| SCHEMBL23686191 | 0.72 | ABCC1 (0.67) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL10747448 | 0.72 | ABCC1 (0.67) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL3326229 | 0.72 | KDM4E (0.78) | GAAMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL11004678 | 0.71 | CACNA1F (0.63) | CACNA1FCACNA1DCACNA1SCACNA1CMEN1 | |
| SCHEMBL7967817 | 0.70 | KDM4E (0.64) | ABCC1CACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | disclosed |