SCHEMBL7968082

SCHEMBL7968082

CC(C(=O)OCCCl)c1cc(N)ccc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2C P28335 1/20 0.39
CHRNA4 P43681 1/20 0.39
HTR3A P46098 1/20 0.39
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
CYP3A4 P08684 6/20 0.35
TSHR P16473 3/20 0.34
SCN1A P35498 1/20 0.33
SCN2A Q99250 1/20 0.33
SCN3A Q9NY46 1/20 0.33
ALOX5 P09917 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PKM P14618 1/20 0.33
LMNA P02545 5/20 0.32
SMN1; SMN2 Q16637 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28796014 0.78 CYP3A4 (0.43) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL28776445 0.75 ALDH1A1 (0.38) CYP3A4TSHRKDM4EMEN1KMT2A
SCHEMBL27558594 0.72 CYP3A4 (0.44) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL3341272 0.72 CYP3A4 (0.44) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL7968087 0.71 CYP3A4 (0.41) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL24586252 0.70 CYP3A4 (0.43) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL19862410 0.69 CYP3A4 (0.48) KCNH2CYP3A4TSHRMEN1KMT2A
SCHEMBL7968084 0.69 TDP1 (0.38) MAOACHRM2CHRM3HTR2CCHRNA4
SCHEMBL1762357 0.69 CYP3A4 (0.52) CYP3A4TSHRKDM4EMEN1KMT2A
SCHEMBL3341280 0.68 MAPT (0.38) MAOACHRM2CHRM3HTR2CCHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed
US-5817603-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed