SCHEMBL7968087

SCHEMBL7968087

CCOC(=O)C(CCl)c1cc(N)ccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.41
MAOA P21397 2/20 0.41
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CHRM2 P08172 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2C P28335 1/20 0.39
CHRNA4 P43681 1/20 0.39
HTR3A P46098 1/20 0.39
KCNH2 Q12809 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
CASP1 P29466 1/20 0.38
CYP2C9 P11712 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
TSHR P16473 2/20 0.37
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27558594 0.84 CYP3A4 (0.44) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL3341272 0.84 CYP3A4 (0.44) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL7767699 0.74 CYP3A4 (0.41) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL7968082 0.71 MAOA (0.39) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL194508 0.71 CYP4F2 (0.63) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL21676593 0.71 CYP3A4 (0.39) CYP3A4MAOACHRM2CHRM3HTR2C
SCHEMBL9734886 0.69 CYP3A4 (0.39) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL4277534 0.69 MAOA (0.44) CYP3A4MAOALMNACYP1A2CHRM2
SCHEMBL21656353 0.69 CASP1 (0.54) CYP3A4CYP1A2CASP1CYP2C9TSHR
SCHEMBL28276253 0.69 CUL4A (0.48) CYP3A4MAOALMNACYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6204222-B1 SUITABLE AS HERBICIDES AND FOR DESICCATION/DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-20 US disclosed
US-5817603-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1998-10-06 US disclosed