Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.55 |
| ▸ | TUBB | P07437 | 2/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268276 | 0.85 | OXER1 (0.62) | ALOX15ALDH1A1HPGDHTTMAPT | |
| SCHEMBL15512501 | 0.85 | OXER1 (0.62) | ALOX15ALDH1A1HPGDHTTMAPT | |
| SCHEMBL3564166 | 0.83 | ALDH1A1 (0.57) | ALOX15TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL3276393 | 0.83 | TUBB4A (0.67) | SMN1; SMN2TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL17616303 | 0.82 | ALDH1A1 (0.63) | ALOX15NPSR1LMNATSHRHSD17B10 | |
| SCHEMBL7211886 | 0.81 | OXER1 (0.53) | ALOX15NPSR1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL9273621 | 0.81 | OXER1 (0.53) | ALOX15NPSR1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2341965 | 0.80 | ALOX15 (0.67) | ALOX15SMN1; SMN2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL7672077 | 0.80 | TUBB4A (0.67) | ALOX15TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL17022468 | 0.79 | OXER1 (0.62) | HSD17B10ALDH1A1HPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310217-B1 | ANTIINFLAMMATORY AND ANALGESIC AGENTS | MERCKLE GMBH (DE) | 2001-10-30 | — | — | US | disclosed |