Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968212 | 1.00 | KMT2A (0.35) | KMT2APOLBMEN1NPC1MAPT | |
| SCHEMBL7968396 | 0.87 | ALDH1A1 (0.36) | KMT2APOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7982001 | 0.87 | ALDH1A1 (0.36) | KMT2APOLBSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7968400 | 0.81 | ALDH1A1 (0.37) | KMT2APOLBMEN1NPC1MAPT | |
| SCHEMBL7968403 | 0.81 | ALDH1A1 (0.37) | KMT2APOLBMEN1NPC1MAPT | |
| SCHEMBL8134544 | 0.81 | ALDH1A1 (0.36) | KMT2APOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8134546 | 0.81 | ALDH1A1 (0.36) | KMT2APOLBMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL7981677 | 0.77 | CTSL (0.39) | KMT2APOLBMEN1MAPTALDH1A1 | |
| SCHEMBL7984627 | 0.73 | ALDH1A1 (0.35) | KMT2APOLBMEN1MAPTSMN1; SMN2 | |
| SCHEMBL7984624 | 0.70 | ALDH1A1 (0.36) | KMT2APOLBMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |