Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8141003 | 1.00 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL8134546 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBMAPTMCOLN3 | |
| SCHEMBL8134544 | 0.78 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBMAPTMCOLN3 | |
| SCHEMBL7968400 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAPOLBMAPTTDP1 | |
| SCHEMBL7968403 | 0.76 | ALDH1A1 (0.37) | ALDH1A1LMNAPOLBMAPTTDP1 | |
| SCHEMBL7981677 | 0.73 | CTSL (0.39) | ALDH1A1LMNAPOLBMAPTTDP1 | |
| SCHEMBL7982001 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBTDP1MCOLN3 | |
| SCHEMBL7968396 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNAPOLBTDP1MCOLN3 | |
| SCHEMBL7984627 | 0.71 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBMAPTMAPK1 | |
| SCHEMBL7968216 | 0.70 | KMT2A (0.35) | ALDH1A1LMNAPOLBMAPTMCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |