Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17231208 | 0.86 | MMP2 (0.34) | MMP2ANPEPTDP1MAPT | |
| SCHEMBL7981677 | 0.82 | CTSL (0.39) | KMT2AMMP2ANPEPNPSR1TDP1 | |
| SCHEMBL7978138 | 0.80 | KMT2A (0.45) | KMT2AHPGDMMP2ANPEPHTT | |
| SCHEMBL17476471 | 0.78 | KDM4E (0.39) | KMT2AHPGDMMP2ANPEPKDM4E | |
| SCHEMBL17476470 | 0.78 | KDM4E (0.39) | KMT2AHPGDMMP2ANPEPKDM4E | |
| SCHEMBL19175459 | 0.77 | KMT2A (0.52) | KMT2AHPGDHTTKDM4EMAPT | |
| SCHEMBL19035896 | 0.77 | MMP2 (0.37) | KMT2AHPGDMMP2ANPEPHTT | |
| SCHEMBL20248626 | 0.77 | MAPT (0.35) | KMT2AMMP2ANPEPTDP1KDM4E | |
| SCHEMBL18313952 | 0.76 | KDM4E (0.41) | KMT2AHPGDHTTKDM4EALDH1A1 | |
| SCHEMBL9520614 | 0.75 | MMP2 (0.43) | HPGDMMP2ANPEPHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6225306-B1 | PYRROLO(1,2A)QUINOXALINES | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |