Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | TP53 | P04637 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5067444 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL187051 | 1.00 | ALDH1A1 (0.66) | ALDH1A1TP53TSHRMAPTHPGD | |
| Ammonia Solution, Strong SCHEMBL11545942 | 0.98 | ALDH1A1 (0.64) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL13383366 | 0.94 | ALDH1A1 (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL13527949 | 0.94 | ALDH1A1 (0.60) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL13330202 | 0.91 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL14062637 | 0.91 | ALDH1A1 (0.57) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL5966311 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL17897424 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRMAPTHPGD | |
| SCHEMBL16640986 | 0.90 | ALDH1A1 (0.55) | ALDH1A1TP53TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109609479-A | A kind of Aspergillus usamii epoxide hydrolase mutant that enantioselectivity improves | 江南大学 | 2019-04-12 | — | — | CN | claimed |
| CN-116790203-A | Itaconic acid deep eutectic solvent and preparation method and application thereof | 华南农业大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-113214455-B | Toughening type water-based epoxy curing agent and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-04-22 | — | — | CN | disclosed |
| CN-113214455-A | Toughening type water-based epoxy curing agent and preparation method and application thereof | 万华化学集团股份有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-109609479-B | Aspergillus usamii epoxide hydrolase mutant with improved enantioselectivity | 江南大学 | 2021-07-27 | — | — | CN | disclosed |
| CN-109609479-A | A kind of Aspergillus usamii epoxide hydrolase mutant that enantioselectivity improves | 江南大学 | 2019-04-12 | — | — | CN | disclosed |
| US-9938222-B2 | Cyclopropanecarboxylic acid GPR120 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-10 | — | — | US | disclosed |
| US-20170253554-A1 | CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-09-07 | — | — | US | disclosed |
| CN-104450641-A | Epoxide hydrolase as well as encoding gene and application thereof | UNIV EAST CHINA SCIENCE & TECH | 2015-03-25 | — | — | CN | disclosed |
| US-6242450-B1 | SUBSTITUTED PIPERIDINES | ELI LILLY AND COMPANY | 2001-06-05 | — | — | US | disclosed |
| WO-2000006082-A2 | TREATMENT OF ANXIETY DISORDERS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| WO-2000006166-A1 | 5-HT1F ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-02-10 | — | — | WO | disclosed |
| EP-0976746-A1 | 5-HT1F antagonists | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976747-A2 | Use of 5HT-1F receptor antagonists for treating anxiety disorders | ELI LILLY AND COMPANY (US) | 2000-02-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253554-A1 | CYCLOPROPANECARBOXYLIC ACID GPR120 MODULATORS | GPR88, GPBAR1, GPR68 | ALDH1A1 2321/4885TP53 4594/4885TSHR 991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.