Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 6/20 | 0.54 |
| ▸ | NCF1 | P14598 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979823 | 0.88 | POLB (0.43) | NPY5RNCF1GAANPC1RAB9A | |
| SCHEMBL7978337 | 0.87 | KMT2A (0.50) | NPY5RNCF1MAPTALDH1A1KMT2A | |
| SCHEMBL7982268 | 0.86 | NPY5R (0.44) | NPY5RNCF1GAAMAPTALDH1A1 | |
| SCHEMBL7981498 | 0.83 | CBFB (0.45) | NPY5RNCF1MAPTALDH1A1HSD17B10 | |
| SCHEMBL7985050 | 0.79 | NPY5R (0.62) | NPY5RNCF1GAAMAPTADRB2 | |
| SCHEMBL7981527 | 0.78 | NPY5R (0.64) | NPY5RNCF1GAAMAPTALDH1A1 | |
| SCHEMBL7981521 | 0.77 | NCF1 (0.36) | NPY5RNCF1GAAMAPTALDH1A1 | |
| SCHEMBL7981525 | 0.76 | NPY5R (0.55) | NPY5RGAAMAPTCYP1A2CYP2D6 | |
| SCHEMBL7978430 | 0.75 | METAP1 (0.36) | NPY5RNCF1MAT2A | |
| SCHEMBL17524931 | 0.75 | MAPT (0.51) | GAAMAPTALDH1A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003744-A1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | claimed |
| WO-1999007703-A1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | claimed |
| US-6187778-B1 | EATING AND CARDIOVASCULAR DISORDERS | PFIZER INC. | 2001-02-13 | — | — | US | disclosed |
| EP-1003744-A1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007703-A1 | 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | disclosed |