Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73543 | 0.82 | AOC3 (0.47) | SLC6A4SLC6A3AOC3NPC1RAB9A | |
| SCHEMBL12534038 | 0.79 | AOC3 (0.41) | SLC6A4SLC6A3AOC3NPC1RAB9A | |
| SCHEMBL3640169 | 0.79 | AOC3 (0.44) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL10441226 | 0.77 | AOC3 (0.42) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL7973510 | 0.76 | SLC6A3 (0.43) | HTR2AKCNH2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1237690 | 0.76 | MAOB (0.49) | HTR2AKCNH2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL29688552 | 0.76 | MAOB (0.49) | HTR2AKCNH2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6087786 | 0.75 | SMYD3 (0.42) | SLC6A4SLC6A3AOC3NPC1RAB9A | |
| SCHEMBL5584506 | 0.75 | AOC3 (0.40) | SLC6A4SLC6A3AOC3NPC1RAB9A | |
| SCHEMBL7203954 | 0.72 | HRH4 (0.53) | HTR2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014374-A2 | PROCESSES FOR THE PREPRATION OF EXO- AND ENDO-INDOLOTROPANES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-03-01 | — | — | WO | disclosed |