Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828820 | 0.71 | — | — | |
| SCHEMBL23499294 | 0.71 | NPC1 (0.35) | NPC1IDH1CA3CA6CA5A | |
| SCHEMBL15637534 | 0.70 | TGFBR1 (0.35) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL2053480 | 0.68 | CA3 (0.33) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL9766850 | 0.67 | CA9 (0.52) | IDH1CA3CA6CA5ACA9 | |
| SCHEMBL15637127 | 0.66 | IDH1 (0.33) | NPC1IDH1CA3CA6CA5A | |
| SCHEMBL403252 | 0.64 | — | — | |
| SCHEMBL7974719 | 0.63 | MKNK1 (0.39) | IDH1 | |
| SCHEMBL9046467 | 0.63 | NPC1 (0.39) | NPC1LMNA | |
| SCHEMBL9566537 | 0.63 | NPC1 (0.68) | NPC1IDH1LMNAAGPAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |