Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.38 |
| ▸ | ME2 | P23368 | 1/20 | 0.38 |
| ▸ | ME1 | P48163 | 1/20 | 0.38 |
| ▸ | ME3 | Q16798 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972602 | 0.86 | KIF11 (0.39) | MAOBKDM4EKIF11CYP1A1CYP1B1 | |
| SCHEMBL6026415 | 0.86 | KDM4E (0.47) | MAOBKDM4ENPC1HPGDRAB9A | |
| SCHEMBL7968717 | 0.86 | KIF11 (0.46) | TP53GPR55KDM4ESMN1; SMN2TDP1 | |
| SCHEMBL7539856 | 0.80 | ABCG2 (0.37) | ABCG2RAB9AKIF11 | |
| SCHEMBL7968670 | 0.77 | KIF11 (0.42) | KDM4EKIF11ALDH1A1 | |
| SCHEMBL6026074 | 0.75 | KDM4E (0.46) | TP53MAOBKDM4ENPC1HPGD | |
| SCHEMBL3992142 | 0.73 | KIF11 (0.54) | TP53MAOBGSK3BRAB9AAHR | |
| SCHEMBL5693270 | 0.72 | KIF11 (0.70) | TP53MAOBGSK3BNPC1RAB9A | |
| SCHEMBL6026701 | 0.71 | EDNRA (0.43) | TP53KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7956413 | 0.71 | CFTR (0.39) | TP53GPR55SMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265436-B1 | ANTIINFLAMMATORY AGENTS | OXIS THERAPEUTICS INC. | 2001-07-24 | — | — | US | disclosed |