Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796926 | 0.82 | KDM4E (0.31) | ALDH1A1KDM4ELMNAMAPK1MAPT | |
| SCHEMBL797664 | 0.79 | TLR8 (0.30) | — | |
| SCHEMBL7197061 | 0.77 | ALDH1A1 (0.35) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL4062027 | 0.75 | ALDH1A1 (0.34) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL1686826 | 0.75 | ALDH1A1 (0.34) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL16424248 | 0.75 | ALDH1A1 (0.34) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| SCHEMBL5355719 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| SCHEMBL7599708 | 0.72 | KDM4E (0.31) | ALDH1A1CYP2A6KDM4ELMNAMAPK1 | |
| SCHEMBL797367 | 0.72 | PBRM1 (0.32) | — | |
| SCHEMBL7889132 | 0.69 | TDP1 (0.31) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785671-B2 | 6,13-dihalogen-5,14-dihydropentacene derivative and method for producing 6,13-substituted-5,14-dihydropentacene derivative using same | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20130079530-A1 | 6,13-DIHALOGEN-5,14-DIHYDROPENTACENE DERIVATIVE AND METHOD FOR PRODUCING 6,13-SUBSTITUTED-5,14-DIHYDROPENTACENE DERIVATIVE USING SAME | NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY | 2013-03-28 | — | — | US | disclosed |
| EP-1262469-B1 | POLYACENE DERIVATIVES AND PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7901594-B2 | Electroconductivity | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-6586554-B1 | Polyarylene and method for production thereof | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20030116755-A1 | Polyacene derivatives and production thereof | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1262469-A1 | POLYACENE DERIVATIVES AND PRODUCTION THEREOF | Japan Science and Technology Corporation (JP) | 2002-12-04 | — | — | EP | disclosed |
| EP-1219657-A1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | Japan Science and Technology Corporation (JP) | 2002-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079530-A1 | 6,13-DIHALOGEN-5,14-DIHYDROPENTACENE DERIVATIVE AND METHOD FOR PRODUCING 6,13-SUBSTITUTED-5,14-DIHYDROPENTACENE DERIVATIVE USING SAME | DHCR7, DHCR24, DHPS | ALDH1A1 2629/4885CYP2A6 37/4885KDM4E 2270/4885 |
| US-20030116755-A1 | Polyacene derivatives and production thereof | CBR1, HVCN1, H1-0 | ALDH1A1 591/4885CYP2A6 822/4885KDM4E 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.