Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721456 | 0.88 | LTA4H (0.42) | TSHRL3MBTL1PPARGPPARAALDH1A1 | |
| SCHEMBL7969039 | 0.84 | TSHR (0.40) | TSHRAKT1HDAC1L3MBTL1ALDH1A1 | |
| SCHEMBL14965801 | 0.81 | TSHR (0.44) | TSHRHDAC1HDAC4HDAC6KDM4E | |
| SCHEMBL3364898 | 0.80 | NPC1 (0.52) | TDP1PTPN1PTPN6PTPN11HDAC1 | |
| SCHEMBL7611509 | 0.78 | NPC1 (0.50) | TDP1PTPN1PTPN6PTPN11NR1D1 | |
| SCHEMBL8575850 | 0.77 | ACHE (0.52) | HCRTR2TDP1TSHRPTPN1PTPN6 | |
| SCHEMBL14215518 | 0.77 | RORC (0.55) | TDP1TSHRPTPN1PTPN6PTPN11 | |
| Bromide SCHEMBL20547060 | 0.77 | NPC1 (0.49) | TDP1PTPN1PTPN6PTPN11NR1D1 | |
| SCHEMBL18045335 | 0.76 | CASP1 (0.47) | HCRTR2TDP1PTPN1PTPN6PTPN11 | |
| SCHEMBL12198408 | 0.75 | NPC1 (0.47) | TDP1PTPN1PTPN6PTPN11HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839828-A1 | Building blocks for DNA/PNA-Cooligomer | BAYER AG (DE) | 1998-05-06 | — | — | EP | disclosed |