Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12909455 | 0.81 | FEN1 (0.45) | FEN1TSHRHSD17B10MAPTALDH1A1 | |
| SCHEMBL7971906 | 0.76 | HTR6 (0.52) | HSD17B10MAPTALDH1A1ACLYLMNA | |
| SCHEMBL7971560 | 0.75 | PSIP1 (0.39) | ALDH1A1NPSR1ACLYLMNANAMPT | |
| SCHEMBL4818876 | 0.75 | TSHR (0.62) | TSHRHSD17B10MAPTALDH1A1RAB9A | |
| SCHEMBL7974914 | 0.75 | HCAR2 (0.38) | ACLYLMNANAMPT | |
| Benzylsulfonylbenzene SCHEMBL780337 | 0.72 | TSHR (0.68) | TSHRHSD17B10MAPTALDH1A1DAO | |
| SCHEMBL29482080 | 0.72 | TSHR (0.58) | TSHRHSD17B10MAPTALDH1A1DAO | |
| SCHEMBL9820015 | 0.72 | MAPT (0.61) | TSHRHSD17B10MAPTALDH1A1RAB9A | |
| SCHEMBL7969245 | 0.71 | CYP2C9 (0.37) | ALDH1A1NPSR1ACLYLMNACYP2D6 | |
| SCHEMBL10973040 | 0.71 | MAPT (0.52) | MAPTALDH1A1RAB9ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |