Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974641 | 0.87 | ALDH1A1 (0.61) | HTR6NAMPTALDH1A1PKMHSD17B10 | |
| SCHEMBL7958556 | 0.82 | NAMPT (0.45) | HTR6NAMPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7969060 | 0.82 | GAA (0.55) | HTR6NAMPTALDH1A1TDP1CYP3A4 | |
| SCHEMBL7974709 | 0.82 | NAMPT (0.45) | HTR6NAMPTALDH1A1CYP3A4MAPK1 | |
| SCHEMBL31109058 | 0.82 | HCAR2 (0.54) | NAMPTACLYALDH1A1MAPK1LMNA | |
| SCHEMBL7974711 | 0.82 | HCAR2 (0.54) | NAMPTACLYALDH1A1MAPK1LMNA | |
| SCHEMBL7974869 | 0.78 | PKM (0.59) | NAMPTPKMHTTLMNAPGR | |
| SCHEMBL27998544 | 0.78 | HTR6 (0.64) | HTR6ALDH1A1PKMHSD17B10TDP1 | |
| SCHEMBL17589590 | 0.78 | CYP11B1 (0.54) | HTR6NAMPTALDH1A1PKMHTT | |
| SCHEMBL5582693 | 0.78 | HTR6 (0.52) | HTR6ALDH1A1FFAR2HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |