SCHEMBL7969322

SCHEMBL7969322

Clc1cncc([CH]c2cnc(Cl)s2)c1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7958255 0.70 NPC1 (0.40) HTTCHRNB2CHRNA4
SCHEMBL7968716 0.67 POLB (0.41) HTTHCAR2CYP1A2CYP2C9CYP2C19
SCHEMBL8436212 0.67 CYP11B2 (0.39) HCAR2
SCHEMBL7971923 0.66 CHRM5 (0.47) CYP1A2CYP2C9CYP2C19
SCHEMBL30966540 0.65
SCHEMBL989986 0.65
SCHEMBL14844098 0.65
SCHEMBL360323 0.65
SCHEMBL335671 0.65
SCHEMBL14676728 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed