Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958570 | 0.76 | CYP11B2 (0.46) | NPC1RAB9AHTTNFE2L2ALDH1A1 | |
| SCHEMBL8491445 | 0.76 | RELA (0.42) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL7968716 | 0.76 | POLB (0.41) | NPC1RAB9AHTTNFE2L2MEN1 | |
| SCHEMBL8436212 | 0.76 | CYP11B2 (0.39) | MAPT | |
| SCHEMBL7971923 | 0.74 | CHRM5 (0.47) | NFE2L2MEN1MAPTKMT2A | |
| SCHEMBL7968962 | 0.72 | CYP11B2 (0.38) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL7975159 | 0.72 | AHR (0.53) | NPC1RAB9AALDH1A1MAPTCYP2A6 | |
| SCHEMBL7958780 | 0.71 | LCK (0.48) | RAB9AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8488964 | 0.71 | VCP (0.40) | NPC1RAB9A | |
| SCHEMBL7969322 | 0.70 | HPGD (0.31) | HTTCHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |