Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 8/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 3/20 | 0.31 |
| ▸ | IDH2 | P48735 | 2/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971991 | 0.78 | KMO (0.38) | HSD17B14KMOCYP3A4TSHRIDH1 | |
| SCHEMBL7974715 | 0.75 | CYP3A4 (0.34) | CYP3A4TSHRPDCD1LG2CD274IDH1 | |
| SCHEMBL28115232 | 0.70 | EGFR (0.40) | HSD17B14KMOCYP3A4GAAL3MBTL1 | |
| SCHEMBL7968303 | 0.70 | SCN9A (0.36) | CYP3A4TSHRLMNAGAAIDH1 | |
| SCHEMBL7958260 | 0.69 | GPBAR1 (0.36) | CYP3A4TSHRGAAL3MBTL1NFE2L2 | |
| SCHEMBL19072698 | 0.69 | TGFBR1 (0.35) | HSD17B14PDCD1LG2CD274 | |
| SCHEMBL7971895 | 0.68 | CYP3A4 (0.36) | CYP3A4TSHRPDCD1LG2CD274L3MBTL1 | |
| SCHEMBL9712454 | 0.67 | SLC2A1 (0.35) | — | |
| SCHEMBL7971525 | 0.66 | CYP3A4 (0.38) | CYP3A4TSHRIDH1IDH2 | |
| SCHEMBL8994176 | 0.66 | CES2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |