SCHEMBL7969633

SCHEMBL7969633

Cc1cc(C)c(-c2[c]cc(Cl)cn2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
RAPGEF4 Q8WZA2 3/20 0.34
KDM4E B2RXH2 1/20 0.31
PKM P14618 1/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7958642 0.71 BRD4 (0.39) MEN1KMT2A
SCHEMBL792214 0.68
SCHEMBL7969444 0.66 MKNK1 (0.37)
SCHEMBL7972246 0.64 CYP1A2 (0.38) MEN1KMT2AKDM4E
SCHEMBL25283007 0.63 ALDH1A1 (0.49) MEN1KMT2AKDM4E
SCHEMBL193034 0.62
SCHEMBL7009262 0.61 RAPGEF4 (0.54) MEN1KMT2ARAPGEF4KDM4E
SCHEMBL2097194 0.60 KDM4E (0.30) KDM4EPKM
SCHEMBL317299 0.60 RAPGEF4 (0.50) RAPGEF4KDM4E
SCHEMBL17229432 0.60 RAPGEF4 (0.46) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed