Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968772 | 0.91 | EBP (0.38) | EBPSIGMAR1L3MBTL1NR3C1EPHX2 | |
| SCHEMBL7965792 | 0.89 | EBP (0.35) | EBPSIGMAR1L3MBTL1NR3C1EPHX2 | |
| SCHEMBL7967090 | 0.88 | ADRA2B (0.41) | EBPSIGMAR1L3MBTL1EPHX2SLC6A2 | |
| SCHEMBL7968665 | 0.87 | EBP (0.38) | EBPSIGMAR1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7967041 | 0.86 | BCHE (0.39) | EBPSIGMAR1L3MBTL1NR3C1EPHX2 | |
| SCHEMBL7966552 | 0.84 | EBP (0.38) | EBPSIGMAR1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7968620 | 0.84 | SIGMAR1 (0.46) | EBPSIGMAR1L3MBTL1NR3C1SLC6A2 | |
| SCHEMBL7956305 | 0.84 | EBP (0.38) | EBPSIGMAR1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7968443 | 0.84 | EBP (0.38) | EBPSIGMAR1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL7971484 | 0.84 | EBP (0.40) | EBPSIGMAR1SLC6A4UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265439-B1 | Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives | G.D. SEARLE & CO. | 2001-07-24 | — | — | US | disclosed |
| US-5451604-A | Useful in organ transplant surgery | G. D. SEARLE & CO. (US) | 1995-09-19 | — | — | US | disclosed |