Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235466 | 0.77 | TP53 (0.46) | LCKPARP1POLBGABRA1GABRA5 | |
| SCHEMBL7982949 | 0.77 | GABRA5 (0.36) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL2468642 | 0.77 | DAO (0.46) | GABRA1GABRG2GABRB3GABRA5GABRA2 | |
| Lithium Ion SCHEMBL31177616 | 0.75 | PARP1 (0.40) | PARP1POLBGABRA5 | |
| SCHEMBL7983014 | 0.74 | GABRA5 (0.46) | LCKALDH1A1POLBMAPTGABRA1 | |
| SCHEMBL29235602 | 0.74 | PARP1 (0.45) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL4763948 | 0.73 | PARP1 (0.59) | PARP1ALDH1A1POLBMAPTGABRA1 | |
| SCHEMBL30095396 | 0.73 | PARP1 (0.59) | PARP1ALDH1A1POLBMAPTGABRA1 | |
| SCHEMBL11557800 | 0.73 | GRIA1 (0.48) | GRIA1GRIA2GRIA3GRIA4PARP1 | |
| SCHEMBL8609965 | 0.71 | CYP1A2 (0.57) | GRIA1GRIA2GRIA3GRIA4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235740-B1 | AUTOIMMUNE DISEASES; ANTIPROLIFERATION AGENTS | BRISTOL-MYERS SQUIBB CO. | 2001-05-22 | — | — | US | disclosed |