Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975832 | 0.97 | L3MBTL1 (0.39) | KMT2AMEN1SMN1; SMN2NPC1MAPT | |
| SCHEMBL7064585 | 0.94 | KMT2A (0.40) | KMT2AMEN1SMN1; SMN2NPC1MAPT | |
| SCHEMBL7973546 | 0.87 | ALDH1A1 (0.44) | KMT2AMEN1SMN1; SMN2CA1CA2 | |
| SCHEMBL7976152 | 0.86 | AR (0.41) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL7975854 | 0.86 | L3MBTL1 (0.47) | KMT2AMEN1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL7976215 | 0.85 | KMT2A (0.38) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL7969761 | 0.85 | KMT2A (0.38) | KMT2AMEN1CA1CA2MMP1 | |
| SCHEMBL7971087 | 0.84 | L3MBTL1 (0.39) | KMT2AMEN1MAPTCA1CA2 | |
| SCHEMBL7959940 | 0.84 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2CA1CA2 | |
| SCHEMBL7970022 | 0.83 | AR (0.41) | KMT2AMEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |