Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959940 | 0.97 | ALDH1A1 (0.43) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7062455 | 0.93 | ALDH1A1 (0.46) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7975854 | 0.90 | L3MBTL1 (0.47) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7969761 | 0.89 | KMT2A (0.38) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7971087 | 0.88 | L3MBTL1 (0.39) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7973313 | 0.87 | L3MBTL1 (0.52) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7970036 | 0.87 | KMT2A (0.38) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7973361 | 0.86 | L3MBTL1 (0.42) | ALDH1A1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7976152 | 0.86 | AR (0.41) | ALDH1A1THRBCA1CA2MMP1 | |
| SCHEMBL7969864 | 0.86 | L3MBTL1 (0.41) | ALDH1A1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |