Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8909907 | 0.76 | PKM (0.36) | PKMMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL27975165 | 0.74 | PKM (0.39) | PKMALDH1A1 | |
| SCHEMBL10355717 | 0.74 | PKM (0.39) | PKMALDH1A1 | |
| SCHEMBL18634221 | 0.74 | — | — | |
| SCHEMBL9725733 | 0.74 | TET2 (0.31) | — | |
| SCHEMBL8536646 | 0.71 | MEN1 (0.30) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL17375347 | 0.70 | ALDH1A1 (0.32) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL3665720 | 0.68 | PKM (0.45) | PKMMEN1ALDH1A1CYP1A2THRB | |
| SCHEMBL7441812 | 0.68 | PKM (0.34) | PKMALDH1A1 | |
| SCHEMBL1187857 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001002357-A2 | PROCESS FOR THE SYNTHESIS OF 4-(4'-FLUOROPHENYL)-PIPERIDINES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-01-11 | — | — | WO | disclosed |