Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.56 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297543 | 0.85 | KDM4E (0.56) | ALDH1A1HTTNPSR1RECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30396830 | 0.84 | KDM4E (0.55) | ALDH1A1HTTNPSR1RECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28961226 | 0.84 | KDM4E (0.55) | ALDH1A1HTTNPSR1RECQLSMN1; SMN2 | |
| SCHEMBL28373626 | 0.83 | TLR8 (0.64) | ALDH1A1HTTNPSR1SAE1UBA2 | |
| SCHEMBL28372897 | 0.83 | TLR8 (0.64) | ALDH1A1HTTNPSR1SAE1UBA2 | |
| SCHEMBL28378368 | 0.83 | TLR8 (0.64) | ALDH1A1HTTNPSR1SAE1UBA2 | |
| SCHEMBL28283760 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HTTNPSR1SAE1UBA2 | |
| SCHEMBL28378028 | 0.82 | TLR8 (0.63) | ALDH1A1HTTNPSR1SAE1UBA2 | |
| SCHEMBL9670397 | 0.81 | KDM4E (0.57) | ALDH1A1HTTNPSR1RECQLSMN1; SMN2 | |
| SCHEMBL20893365 | 0.80 | RAB9A (0.57) | ALDH1A1HTTRECQLSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |