Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969951 | 0.88 | CYP2D6 (0.62) | CYP2D6ALDH1A1LMNAHSD11B1SMN1; SMN2 | |
| SCHEMBL14817973 | 0.85 | CYP2D6 (0.65) | CYP2D6ALDH1A1LMNAHSD11B1HTT | |
| SCHEMBL7958924 | 0.85 | S1PR2 (0.55) | CYP2D6ALDH1A1HSD11B1HTTCA12 | |
| SCHEMBL7972857 | 0.85 | HSD11B1 (0.62) | CYP2D6HSD11B1CA12CA1CA2 | |
| SCHEMBL7975189 | 0.84 | CYP2D6 (0.62) | CYP2D6ALDH1A1HSD11B1CA12CA1 | |
| SCHEMBL9185373 | 0.84 | CYP2D6 (0.62) | CYP2D6ALDH1A1HSD11B1HTTALOX15 | |
| SCHEMBL7970388 | 0.84 | CYP2D6 (0.62) | CYP2D6ALDH1A1HSD11B1MAPK1CA12 | |
| SCHEMBL7970184 | 0.83 | CYP2D6 (0.61) | CYP2D6ALDH1A1HSD11B1CA12CA1 | |
| SCHEMBL7972315 | 0.82 | ALDH1A1 (0.52) | CYP2D6ALDH1A1SMN1; SMN2HTTHPGD | |
| SCHEMBL7972620 | 0.82 | CYP2D6 (0.60) | CYP2D6ALDH1A1LMNAHSD11B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |