Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5360736 | 0.99 | ACHE (0.50) | ACHEHTR7HTR1ACACNA1GALDH1A1 | |
| SCHEMBL7984579 | 0.91 | ACHE (0.52) | ACHEHTR7HTR1AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL5364551 | 0.90 | ACHE (0.51) | ACHEHTR7HTR1AALDH1A1TSHR | |
| SCHEMBL7980861 | 0.88 | ACHE (0.53) | ACHEHTR7HTR1AALDH1A1TSHR | |
| SCHEMBL222020 | 0.77 | ACHE (0.56) | ACHE | |
| SCHEMBL14577909 | 0.77 | ACHE (0.54) | ACHEHTR7HTR1AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9050783 | 0.76 | MAPT (0.49) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL14578069 | 0.76 | KMT2A (0.51) | ALDH1A1KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5353029 | 0.76 | ACHE (0.53) | ACHEHTR7HTR1AALDH1A1TSHR | |
| SCHEMBL6958000 | 0.76 | MAPT (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173132-B2 | Certain substituted 1-aryl-3-piperazine-1′-yl propanones | MOLECULAR GERIATRICS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173132-B2 | Certain substituted 1-aryl-3-piperazine-1′-yl propanones | MOLECULAR GERIATRICS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |