Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5364551 | 0.99 | ACHE (0.51) | ACHEALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL7970723 | 0.91 | ACHE (0.51) | ACHEALDH1A1KMT2AKDM4ETSHR | |
| Hydrochloric Acid SCHEMBL5360736 | 0.90 | ACHE (0.50) | ACHEALDH1A1KMT2AKDM4ETSHR | |
| SCHEMBL7980861 | 0.89 | ACHE (0.53) | ACHEALDH1A1KMT2ATSHRMEN1 | |
| SCHEMBL222020 | 0.86 | ACHE (0.56) | ACHE | |
| SCHEMBL14578069 | 0.85 | KMT2A (0.51) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL5353257 | 0.85 | KMT2A (0.50) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL6598932 | 0.80 | HTR1A (0.61) | ALDH1A1KMT2AMEN1HTR1A | |
| Hydrochloric Acid SCHEMBL6597392 | 0.79 | HTR1A (0.60) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL14577909 | 0.78 | ACHE (0.54) | ACHEALDH1A1KMT2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | claimed |
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |