Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5353029 | 0.99 | ACHE (0.53) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5357708 | 0.82 | KMT2A (0.56) | ALDH1A1KMT2AMEN1HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL5373255 | 0.79 | ALDH1A1 (0.62) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7980861 | 0.79 | ACHE (0.53) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7984579 | 0.78 | ACHE (0.52) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5364551 | 0.77 | ACHE (0.51) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL7970723 | 0.77 | ACHE (0.51) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5360736 | 0.76 | ACHE (0.50) | ACHEALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL4512612 | 0.76 | ALDH1A1 (0.71) | ACHEALDH1A1KMT2AHTR7HTR1A | |
| SCHEMBL5373264 | 0.76 | ALDH1A1 (0.67) | ACHEALDH1A1KMT2AHTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173132-B2 | Certain substituted 1-aryl-3-piperazine-1′-yl propanones | MOLECULAR GERIATRICS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-7173132-B2 | Certain substituted 1-aryl-3-piperazine-1′-yl propanones | MOLECULAR GERIATRICS CORPORATION (US) | 2007-02-06 | — | — | US | disclosed |