SCHEMBL7970779

SCHEMBL7970779

CC(Cc1ccc(C#N)cc1)(NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 1/20 0.59
ITGA2B P08514 1/20 0.59
CTSS P25774 8/20 0.54
CTSL P07711 6/20 0.47
CTSB P07858 4/20 0.47
P2RX7 Q99572 1/20 0.45
CTSK P43235 3/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TACR1 P25103 1/20 0.43
MAOB P27338 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7970782 1.00 ITGB3 (0.59) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL10654800 0.89 ITGB3 (0.60) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL28199355 0.89 ITGB3 (0.60) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL10655573 0.89 ITGB3 (0.60) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL540182 0.88 CTSS (0.49) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL17066826 0.88 CTSS (0.49) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL540183 0.88 CTSS (0.49) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL13142972 0.87 CTSS (0.48) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL2402469 0.86 ITGB3 (0.59) ITGB3ITGA2BCTSSCTSLCTSB
SCHEMBL8101144 0.86 ITGB3 (0.59) ITGB3ITGA2BCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US disclosed
EP-1043309-A1 Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives LG Chemical Ltd. (KR) 2000-10-11 EP disclosed