Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654800 | 1.00 | ITGB3 (0.60) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL10655573 | 1.00 | ITGB3 (0.60) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL2402469 | 0.94 | ITGB3 (0.59) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL8101144 | 0.94 | ITGB3 (0.59) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL2406040 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL7970782 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL11507944 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL7970779 | 0.89 | ITGB3 (0.59) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL1150931 | 0.88 | CTSS (0.57) | ITGB3ITGA2BCTSSMEN1KMT2A | |
| SCHEMBL5970504 | 0.88 | CTSS (0.57) | ITGB3ITGA2BCTSSMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735400-B | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-108047268-B | 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application | 中国科学技术大学 | 2020-05-01 | — | — | CN | disclosed |
| CN-107735400-A | Cyclic sulfamoyl arylamide derivatives and their use as medicaments for the treatment of hepatitis B | 爱尔兰詹森科学公司 | 2018-02-23 | — | — | CN | disclosed |