Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970947 | 1.00 | HTR1A (0.50) | HTR1ADRD4DRD2HTR2AHTR7 | |
| SCHEMBL6600129 | 0.91 | HTR1A (0.55) | HTR1ADRD4DRD2HTR7ADRA1A | |
| SCHEMBL6600132 | 0.91 | HTR1A (0.55) | HTR1ADRD4DRD2HTR7ADRA1A | |
| SCHEMBL6598932 | 0.89 | HTR1A (0.61) | HTR1ADRD4DRD2HTR1DKMT2A | |
| Hydrochloric Acid SCHEMBL6597392 | 0.88 | HTR1A (0.60) | HTR1ADRD4DRD2HTR2AHTR7 | |
| SCHEMBL6598221 | 0.79 | HTR1A (0.62) | HTR1ADRD2HTR2AHTR7ADRA1A | |
| Hydrochloric Acid SCHEMBL6599492 | 0.78 | HTR1A (0.66) | HTR1ADRD2HTR2AHTR7ADRA1A | |
| SCHEMBL8120660 | 0.78 | DRD4 (0.58) | HTR1ADRD4DRD2ADRA1AHTR1D | |
| SCHEMBL6351477 | 0.76 | DRD4 (0.76) | HTR1ADRD4DRD2HTR2AADRA1A | |
| SCHEMBL6351475 | 0.76 | DRD4 (0.76) | HTR1ADRD4DRD2HTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |